3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester

68181-17-9.png
CAS Number

68181-17-9

Empirical Formula (Hill Notation)

C12H12N2O4S2

Molecular Weight

312.36

Specifications

assay ≥95%
mp 84-86 °C(lit.)
form powder
solubility acetone: soluble50 mg/mL
DMF: soluble
storage temp. −20°C

Safety Information

Symbol

GHS07

Signal word

Warning

EC Number

269-034-3

Hazard statements

H315-H319-H335

Risk Statements (Europe)

36/37/38

Hazard Codes (Europe)

Xi

Safety Statements (Europe)

26-36

WGK Germany

3

Application

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH . (.-.). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH . (.-.). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Incorporates atom linker.